X0708 D LIVE 0002154207 270 Life Sciences Private Capital Fund II (US) LP 390 MADISON AVENUE 27TH FLOOR NEW YORK NY NEW YORK 10017 212-464-1649 DELAWARE None None Limited Partnership true 2026 N/A 270 Life Sciences Private Capital Fund II GP Ltd. 390 Madison Avenue 27th Floor New York NY NEW YORK 10017 Director Gaurav Gupta J.P. Morgan Investment Management Inc. 390 Madison Avenue, 27th Floor New York NY NEW YORK 10017 Executive Officer Stephen Squinto J.P. Morgan Investment Management Inc. 390 Madison Avenue, 27th Floor New York NY NEW YORK 10017 Executive Officer Patrick McGoldrick J.P. Morgan Investment Management Inc. 390 Madison Avenue, 27th Floor New York NY NEW YORK 10017 Executive Officer Samantha Beattie J.P. Morgan Investment Management Inc. 390 Madison Avenue, 27th Floor New York NY NEW YORK 10017 Executive Officer Pooled Investment Fund Venture Capital Fund false Decline to Disclose 06b 3C 3C.1 3C.7 false true true true false 0 J.P. Morgan Securities LLC 79 None None 390 Madison Avenue New York NY NEW YORK 10017 All States false J.P. Morgan Institutional Investments Inc. 102920 None None 277 Park Avenue, Floor 23 New York NY NEW YORK 10172 All States false Indefinite 0 Indefinite The general partner of the Issuer reserves the right to offer a greater or lesser amount of limited partner interests. Total Offering Amount and Total Remaining to be Sold are aggregated with 270 Life Sciences Private Capital Fund II (Cayman) LP. false 0 0 true 0 true 0 true The special limited partner is entitled to carried interest. The investment manager is entitled to a management fee. The carried interest and management fee are fully discussed in the Issuer's confidential offering materials. false 270 Life Sciences Private Capital Fund II (US) LP /s/ Samantha Beattie Samantha Beattie Executive Director of the Investment Manager 2026-09-15