X0708 D LIVE 0002131527 Janus Henderson Biotech Innovation Fund Ltd C/O MAPLES CORPORATE SERVICES LTD BOX 309, UGLAND HOUSE GRAND CAYMAN E9 CAYMAN ISLANDS KY1-1104 345-949-8066 CAYMAN ISLANDS None None Other Cayman Islands exempted company true 2021 N/A Janus Henderson Investors US LLC 151 Detroit Street Denver CO COLORADO 80206 Promoter Investment Manager of the Issuer Hugh Ward c/o Maples Corporate Services Limited P.O. Box 309, Ugland House Grand Cayman E9 CAYMAN ISLANDS KY1-1104 Director Toby Hiscock c/o Maples Corporate Services Limited P.O. Box 309, Ugland House Grand Cayman E9 CAYMAN ISLANDS KY1-1104 Director Matteo Candolfini c/o Maples Corporate Services Limited P.O. Box 309, Ugland House Grand Cayman E9 CAYMAN ISLANDS KY1-1104 Director Kenneth Lubbock c/o Maples Corporate Services Limited P.O. Box 309, Ugland House Grand Cayman E9 CAYMAN ISLANDS KY1-1104 Director Pooled Investment Fund Other Investment Fund false Decline to Disclose 06b 3C 3C.7 false 2021-10-29 true true false 100000 Indefinite 441173044 Indefinite false 81 0 0 0 false Janus Henderson Biotech Innovation Fund Ltd Linda Ruan Linda Ruan Compliance Officer 2026-06-09