X0708 D LIVE 0001823388 Duke Street Bio Ltd 2 DUKE STREET LONDON X0 UNITED KINGDOM W1U 3EH 44-203-8908710 UNITED KINGDOM DS Bio Ltd Other A UK private limited company. true Peter Trill 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Director Phillip Cowley 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Director Alan Wise 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Director Donnie Christian 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Director Harvey McGrath 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Director Barry McGuinness 2 Duke Street London X0 UNITED KINGDOM W1U 3EH Executive Officer Biotechnology Decline to Disclose 06b false 2026-05-15 false true false 0 4136978 4136978 0 The offering amount was GBP3,100,021.00 The exchange rate used was 1GBP = USD1.3345. false 2 0 0 1541309 true $442,078, the portion of the proceeds of this offering from U.S. investors will be paid to Directors over 17 months, comprising salary, benefits and social security contributions. The exchange rate used was 1GBP = USD1.3329 false Duke Street Bio Ltd /s/ Alan Wise Alan Wise Chief Executive Officer 2026-06-11